Informasjon

PCOS (Polycystisk ovariesyndrom)

Prognose ved PCOS

Mange er helt friske og lever et godt liv med PCOS. Alle symptomer og plager man opplever skyldes ikke PCOS, men det er noen sykdommer og tilstander som forekommer oftere hos kvinner med PCOS sammenlignet med andre. PCOS er ikke årsaken til disse sykdommene, men det kan finnes felles underliggende faktorer.

Følgende tilsander forekommer oftere hos PCOS:

Diabetes type 2
Høyt blodtrykk
Hjerte-/kar sykdom
Forhøyet kolesterol
Ikke-alkoholisk fettleversykdom
Migrene
Astma
Depresjon
Angst
Spiseforstyrrelser

Dette dokumentet er basert på det profesjonelle dokumentet "Polycystisk ovariesyndrom". Referanselisten for dette dokumentet vises nedenfor.

International evidence- based guideline for the assessment and management of polycystic ovary syndrome. Monash University on behalf of the NHMRC, Centre for Research Excellence in PCOS and the Australian PCOS Alliance; Melbourne:2018 www.monash.edu
Vanky E. et al. PCOS (Polycystisk ovariesyndrom). Norsk gynekologisk forening Veileder i gynekologi (2021). ePub. ISBN 978-82-692382-1-1. [hentet 22. juni 2021]. www.legeforeningen.no
Taponen S, Martikainen H, Jarvelin MR, et al. Hormonal profile of women with self-reported symptoms of oligomenorrhea and/or hirsutism: Northern Finland birth cohort 1966 study. J.Clin.Endocrinol.Metab. 2003;88(1):141-47. pmid: 12519843 PubMed
March WA, Moore VM, Willson KJ, Phillips DI, Norman RJ, Davies MJ. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum.Reprod. 2010;25(2):544-551. pmid: 19910321 PubMed
Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz BO. The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod. 2016;31(12):2841-2855. PMID: 27664216 PubMed
Eilertsen TB, Vanky E, Carlsen SM. Increased prevalence of diabetes and polycystic ovary syndrome in women with a history of preterm birth: a case-control study. BJOG. 2012;119(3):266-275. pmid: 22168920 PubMed
Pinola P, Piltonen TT, Puurunen J, et al. Androgen Profile Through Life in Women With Polycystic Ovary Syndrome: A Nordic Multicenter Collaboration Study. J Clin Endocrinol Metab. Sep 2015;100(9):3400-3407. PubMed
Randeva HS, Tan BK, Weickert MO, et al. Cardiometabolic aspects of the polycystic ovary syndrome. Endocr Rev. Oct 2012;33(5):812-841. PubMed
Hutchison SK, Stepto NK, Harrison CL, Moran LJ, Strauss BJ, Teede HJ. Effects of exercise on insulin resistance and body composition in overweight and obese women with and without polycystic ovary syndrome. J Clin Endocrinol Metab. Jan 2011;96(1):E48-56. PubMed
Moran LJ, Misso ML, Wild RA, Norman RJ. Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod Update. Jul-Aug 2010;16(4):347-363.
Joham AE, Ranasinha S, Zoungas S, Moran L, Teede HJ. Gestational diabetes and type 2 diabetes in reproductive-aged women with polycystic ovary syndrome. J Clin Endocrinol Metab. Mar 2014;99(3):E447-452. PubMed
Lim SS, Hutchison SK, Van Ryswyk E et al. Lifestyle changes in women with polycystic ovary syndrome. Cochrane Database of Systematic Reviews 2019, Issue 3. Art. No.: CD007506. DOI: 10.1002/14651858.CD007506.pub4. Accessed 24 June 2021. The Cochrane Library
Moran LJ, Noakes M, Clifton PM, Tomlinson L, Galletly C, Norman RJ. Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome. J Clin Endocrinol Metab. Feb 2003;88(2):812-819. PubMed
Legro RS. Obesity and PCOS: implications for diagnosis and treatment. Semin Reprod Med. Dec 2012;30(6):496-506. pmid: 23074008 PubMed
Dumesic DA, Lobo RA. Cancer risk and PCOS. Steroids. Aug 2013;78(8):782-785. PubMed
Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol. 2011 Apr;7(4):219-31. Epub 2011 Jan 25. PMID: 21263450.
Underdal MO, Salvesen O, Henriksen AH et al. Impaired Respiratory Function in Women With PCOS Compared With Matched Controls From a Population-Based Study. J Clin Endocrinol Metabol 2020. pmid:31613965 PubMed
Torvinen A, Koivunen R, Pouta A, et al. Metabolic and reproductive characteristics of first-degree relatives of women with self-reported oligo-amenorrhoea and hirsutism. Gynecol Endocrinol. Sep 2011;27(9):630-635. PubMed
McCartney CR, Prendergast KA, Chhabra S, et al. The association of obesity and hyperandrogenemia during the pubertal transition in girls: obesity as a potential factor in the genesis of postpubertal hyperandrogenism. J Clin Endocrinol Metab. May 2006;91(5):1714-1722. PubMed
Mansson M, Holte J, Landin-Wilhelmsen K, Dahlgren E, Johansson A, Landen M. Women with polycystic ovary syndrome are often depressed or anxious--a case control study. Psychoneuroendocrinology. Sep 2008;33(8):1132-1138. PubMed
Scaruffi E, Gambineri A, Cattaneo S, Turra J, Vettor R, Mioni R. Personality and psychiatric disorders in women affected by polycystic ovary syndrome. Front Endocrinol (Lausanne). 2014;5:185. PubMed
Moran LJ, Pasquali R, Teede HJ, Hoeger KM, Norman RJ. Treatment of obesity in polycystic ovary syndrome: a position statement of the Androgen Excess and Polycystic Ovary Syndrome Society. Fertil Steril. Dec 2009;92(6):1966-1982. PubMed
Morin-Papunen L, Rantala AS, Unkila-Kallio L, et al. Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial. J Clin Endocrinol Metab. May 2012;97(5):1492-1500. PubMed
Kjotrod SB, Carlsen SM, Rasmussen PE, et al. Use of metformin before and during assisted reproductive technology in non-obese young infertile women with polycystic ovary syndrome: a prospective, randomized, double-blind, multi-centre study. Hum Reprod. 2011;26(8):2045-53. pmid: 21606131 PubMed
Vanky E, Zahlsen K, Spigset O, Carlsen SM. Placental passage of metformin in women with polycystic ovary syndrome. Fertil Steril. 2005;83(5):1575-78. pmid: 15866611 PubMed
Given JE, Loane M, Garne E, et al.. Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study.. BMJ 2018; 361: k2477. pmid:29941493 PubMed
Løvvik TS, Carlsen SM, Salvesen Ø et al. Metformin treatment of pregnant women with polycystic ovary syndrome: results of a randomized, controlled, clinical trial. Lancet Diabetes Endocrinol 2019. In press.
Hanem LGE, Salvesen O, Juliusson PB et al. Intrauterine metformin exposure and offspring cardiometabolic risk factors (PedMet study): a 5-10 year follow-up of the PregMet randomised controlled trial. Lancet Child Adolesc 2019; 3(3): 166-74. pmid:30704873 PubMed
Bird ST, Hartzema AG, Brophy JM et al. Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis. CMAJ. Feb 5 2013;185(2):E115-120. pmid: 23209115 PubMed
Gambineri A, Patton L, Altieri P, et al. Polycystic ovary syndrome is a risk factor for type 2 diabetes: results from a long-term prospective study. Diabetes. Sep 2012;61(9):2369-2374. PubMed
Vgontzas AN, Legro RS, Bixler EO at al. Polycystic ovary syndrome is associated with obstructive sleep apnea and daytime sleepiness: role of insulin resistance. J Clin Endocrinol Metab. Feb 2001;86(2):517-20. pmid: 11158002 PubMed
Pergialiotis V, Konstantopoulos P, Prodromidou A. MANAGEMENT OF ENDOCRINE DISEASE: The impact of subclinical hypothyroidism on anthropometric characteristics, lipid, glucose and hormonal profile of PCOS patients: a systematic review and meta-analysis. Eur J Endocrinol 2017; 176(3): R159-66. pmid:28007842 PubMed
Yu HF, Chen HS, Rao DP, Gong J. Association between polycystic ovary syndrome and the risk of pregnancy complications: A PRISMA-compliant systematic review and meta-analysis. Medicine (Baltimore) 2016; 95(51): e4863. pmid:28002314 PubMed
Qin JZ, Pang LH, Li MJ et al. Obstetric complications in women with polycystic ovary syndrome: a systematic review and meta-analysis. Reprod Biol Endocrinol 2013; 11: 56. pmid:23800002 PubMed
Koivunen R, Pouta A, Franks S, et al. Fecundability and spontaneous abortions in women with self-reported oligo-amenorrhea and/or hirsutism: Northern Finland Birth Cohort 1966 Study. Hum Reprod. Sep 2008;23(9):2134-2139. PubMed

Er du helsepersonell?

Ved å oppgi dette kan du få bedre tilpasset innhold om du har formell helsefaglig kompetanse

Mest lest i dag

Kun for helsepersonell

Kan hjertet overbelastes ved idrettsaktiviteter?

Er all fysisk aktivitet sunt for hjertet? En oversiktsartikkel i NEJM Evidence har sett på forskningen innenfor dette temaet.

Psykisk helse

Forskere har funnet en måte å oppdage en narsissist

Finske forskere har eksperimentert seg fram til en måte å oppdage om en person har en narsissistisk personlighetsforstyrrelse.

Familie

Når skal barnet legge seg?

Her er en pekepinn på hva barn i ulike aldre trenger av søvn i døgnet. Og når de bør legge seg for for natta.

PCOS (Polycystisk ovariesyndrom)

Hopp til innhold

Prognose ved PCOS

Er du helsepersonell?

Mest lest i dag

Kan hjertet overbelastes ved idrettsaktiviteter?

Forskere har funnet en måte å oppdage en narsissist

Når skal barnet legge seg?

Informasjon

Hold deg oppdatert

PCOS (Polycystisk ovariesyndrom)

Hopp til innhold

Prognose ved PCOS

Er du helsepersonell?

Andre leste også dette

PCOS, graviditet

PCOS, behandling

Sjeldne menstruasjoner (oligomenoré), veiviser

Mest lest i dag

Kan hjertet overbelastes ved idrettsaktiviteter?

Forskere har funnet en måte å oppdage en narsissist

Når skal barnet legge seg?