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Behandling av astma hos barn

Teofyllin

Teofyllin virker ved at muskulaturen i bronkiene slappes av slik at åpningen i luftrøret blir større. Medisinen ble brukt til å behandle astma hos barn tidligere, men bruk av teofyllin til barn < 12 år frarådes nå.

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Dette dokumentet er basert på det profesjonelle dokumentet "Astma hos barn". Referanselisten for dette dokumentet vises nedenfor.

Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2018. Available from: www.ginasthma.org ginasthma.org
Asher MI, Montefort S, Björkstén B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 2006; 368(9537): 733-43. pmid:16935684 PubMed
Pearce N, Aït-Khaled N, Beasley R, et al. Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2007; 62(9): 758-66. pmid:17504817 PubMed
Rød G, Øymar K, Skadberg B. Astma bronkiale. Norsk barnelegeforening. Generell veileder i pediatri. Revidert 2009 www.helsebiblioteket.no
Akar HH, Tahan F, Gungor HE. The association of forced expiratory volume in one second and forced expiratory flow at 50% of the vital capacity, peak expiratory flow parameters, and blood eosinophil counts in exercise-induced bronchospasm in children with mild asthma. Asia Pac Allergy 2015 Apr; 5(2): 98-102. doi:10.5415/apallergy.2015.5.2.98 DOI
Riedler J, Braun-Fahrländer C, Eder W, Schreuer M, et al. Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey . Lancet 2001; 358: 1129-33. PubMed
Moffatt MF, Gut IG, Demenais F, et al. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 2010; 363: 1211-21. New England Journal of Medicine
Norsk forening for allmennmedisin: Astmaveileder for allmennpraksis, 2015. www.legeforeningen.no
Liu AH. Hygiene theory and allergy and asthma prevention. Paediatr Perinat Epidemiol 2007 Nov; 21 Suppl 3: 2-7. pmid:17935569 PubMed
Ker J, Hartert TV. The atopic march: what's the evidence?. Ann Allergy Asthma Immunol 2009 Oct; 103(4): 282-9. pmid:19852191 PubMed
Mener DJ, Lin SY. Improvement and prevention of asthma with concomitant treatment of allergic rhinitis and allergen-specific therapy. Int Forum Allergy Rhinol 2015; 5 Suppl 1: 45-50. pmid:26072703 PubMed
Goksör E, Loid P, Alm B, et al.. The allergic march comprises the coexistence of related patterns of allergic disease not just the progressive development of one disease. Acta Paediatr 2016 Dec; 105(12): 1472-1479. pmid:27381249 PubMed
Sánchez-García S, Rodríguez del Río P, Escuerdo C, et al. Exercise-induced bronchospasm diagnosis in children. Utility of combined lung function tests. Pediatr Allergy Immunol 2015 Feb; 26(1): 73-9. pmid:25444583 PubMed
van der Hulst AE, Klip H, Brand PL. Risk of developing asthma in young children with atopic eczema: A systematic review. J Allergy Clin Immunol 2007; 120: 565-9. PubMed
Renzetti G, Silvestre G, D'Amario, et al. Less air pollution leads to rapid reduction of airway inflammation and improved airway function in asthmatic children. Pediatrics 2009 Mar; 123(3): 1051-8. pmid:19255039 PubMed
Lu KD, Manoukian K, Radom-Aizik S, et al. Obesity, Asthma, and Exercise in Child and Adolescent Health. Pediatr Exerc Sci 2015; Nov 30: Epub ahead of print. pmid:26618409 PubMed
Örtqvist AK, Lundholm C, Kieler H, et al. Antibiotics in fetal and early life and subsequent childhood asthma: nationwide population based study with sibling analysis. BMJ 2014; 349: g6979.
Etminan M, Sadatsafavi M, Jafari S, et al. Acetaminophen use and the risk of asthma in children and adults: a sytematic review and metaanalysis. Chest 2009; 136: 1316-23. PubMed
Lowe AJ, Carlin JB, Bennett CM, et al. Paracetamol use in early life and asthma: prospective birth cohort study. BMJ 2010; 341: c4616. BMJ (DOI)
Robinson P, Chang AC. Asthma in children. BMJ Best Practice. Last updated Oct 05, 2015. bestpractice.bmj.com
Kemp JP, Kemp JA. Management of asthma in children published correction appears in Am Fam Physician 2002; 65:386. Am Fam Physician 2001; 63:1341-8, 1353-4. American Family Physician
Mintz M. Asthma updage: Part II. Medical management. Am Fam Physicians 2004; 70: 1061-6. PubMed
Bruun Mikalsen I, Karlstad Ø, Furu K, Øymar K. Forskrivning av legemidler mot astma til barn i perioden 2004–15. Tidsskr Nor Legeforen 2018; 4; 138: 345-51. doi:10.4045/tidsskr.17.0227 DOI
Cates CJ, Welsh EJ, Rowe BH. Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma. Cochrane Database of Syst. Rev. 2013, Issue 9. Art. No.: CD000052. DOI: 10.1002/14651858.CD000052.pub3. DOI
Chauhan BF, Chartrand C, Ni Chroinin M, et al. Addition of long-acting beta2-agonists to inhaled corticosteroids for chronic asthma in children. Cochrane Database of Syst Rev 2015, Issue 11. Art. No.: CD007949. DOI: 10.1002/14651858.CD007949.pub2. DOI
Griffiths B, Ducharme FM. Combined inhaled anticholinergics and short-acting beta2-agonists for initial treatment of acute asthma in children. Cochrane Database of Syst Rev 2013, Issue 8. Art. No.: CD000060. DOI: 10.1002/14651858.CD000060.pub2 DOI
Vezina K, Chauhan BF, Ducharme FM. Inhaled anticholinergics and short-acting beta(2)-agonists versus shortacting beta2-agonists alone for children with acute asthma in hospital. Cochrane Database Syst Rev 2014;7:Cd010283 Cochrane (DOI)
Rowe BH, Spooner C, Ducharme FM, Bretzlaff JA, Bota GW. Early emergency department treatment of acute asthma with systemic corticosteroids (Cochrane review). Cochrane Database Syst Rev 2004; (4): CD002178. Cochrane (DOI)
Smith M, Iqbal S, Elliott TM, Rowe BH. Corticosteroids for hospitalised children with acute asthma (Cochrane review). Cochrane Database Syst Rev 2004; (4): CD002886. Cochrane (DOI)
Norsk barnelegeforening: Akuttveileder i pediatri. Akutt astma bronkiale. Sist revidert 2012 (Lødrup Carlsen KC, et al.). Siden besøkt 20.02.2018. www.helsebiblioteket.no
Ducharme FM, Chabot G, Polychronakos C, Glorieux F, Mazer B. Safety profile of frequent short courses of oral glucocorticoids in acute pediatric asthma: impact on bone metabolism, bone density, and adrenal function. Pediatrics 2003; 111: 376-83. Pediatrics
Chang AB, Clark R, Sloots TP, et al. A 5- versus 3-day course of oral corticosteroids for children with asthma exacerbations who are not hospitalized: a randomized controlled trial. Med J Aust 2008; 189: 306-10. PubMed
Keeney GE, Gray MP, Morrison AK, et al. Dexamethasone for acute asthma exacerbations in children: a meta-analysis.Pediatrics. 2014 Mar;133(3):493-9. doi: 10.1542/peds.2013-2273.
Edmonds ML, Milan SJ, Camargo Jr CA, Pollack CV, Rowe BH. Early use of inhaled corticosteroids in the emergency department treatment of acute asthma. Cochrane Database of Systematic Reviews 2012, Issue 12. Art. No.: CD002308. DOI: 10.1002/14651858.CD002308.pub2 DOI
Keeley D, McKean M. Asthma and other wheezing disorders of childhood. Clin Evid 2003; 9: 287-317. Clinical Evidence
Powell C, Kolamunnage-Dona R, Lowe J, et al. MAGNEsium Trial In Children (MAGNETIC): a randomised, placebo-controlled trial and economic evaluation of nebulised magnesium sulphate in acute severe asthma in children. Health Technol Assess 2013; 17: 1-216. doi:10.3310/hta17450 DOI
Powell C, Dwan K, Milan SJ, et al. Inhaled magnesium sulfate in the treatment of acute asthma. Cochrane Database Syst Rev 2012;12:CD003898 Cochrane (DOI)
National Asthma Education and Prevention Program. Expert panel report. Guidelines for the diagnosis and management of asthma: update on selected topics, 2002. Bethesda, Md.: U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Heart, Lung, and Blood Institute, 2003; NIH publication no. 02-5074.
Chauhan BF, Ducharme FM. Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. Cochrane Database of Syst Rev 2012, Issue 5. Art. No.: CD002314. DOI: 10.1002/14651858.CD002314.pub3 DOI
Kelly HW, Sternberg AL, Lescher R, et al. Effect of inhaled glucocorticoids in childhood on adult height. N Engl J Med 2012; 367: 904-12. Pmid:22938716 PubMed
Zhang L, Prietsch SOM, Ducharme FM. Inhaled corticosteroids in children with persistent asthma: effects on growth. Cochrane Database of Systematic Reviews 2014, Issue 7. Art. No.: CD009471. DOI: 10.1002/14651858.CD009471.pub2. DOI
Guilbert TW, Morgan WJ, Zeiger RS, et al. Long-term inhaled corticosteroids in preschool children at high risk for asthma. N Engl J Med 2006; 354: 1985-97. doi:10.1056/NEJMoa051378 DOI
Guilbert TW, Mauger DT, Allen DB, et al. Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone. J Allergy Clin Immunol 2011 Nov; 128(5): 956-63. doi:10.1016/j.jaci.2011.06.027 DOI
Chauhan BF, Chartrand C, Ducharme FM. Intermittent versus daily inhaled corticosteroids forpersistent asthma in children and adults. Cochran Database Syst Rev 2013; 2: CD009611. pmid:23450606 PubMed
Bisgaard H, Hermansen MN, Loland L, Halkjaer LB, Buchvald F. Intermittent inhaled corticosteroids in infants with episodic wheezing. N Engl J Med 2006; 354: 1998-2005. New England Journal of Medicine
Chauhan BF, Ben Salah R, Ducharme FM. Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma. Cochrane Database of Syst Rev 2013, Issue 10. Art. No.: CD009585. DOI: 10.1002/14651858.CD009585.pub2. DOI
Robertson CF, Price D, Henry R, et al. Short-course montelukast for intermittent asthma in children: a randomized controlled trial. Am J Respir Crit Care Med 2007; 175: 323-9. PubMed
Busse WW, Morgan WJ, Gergen PJ, et al. Randomized trial of omalizumab (Anti-IgE) for astma in inner-city children. N Engl J Med 2011; 364: 1005-15. New England Journal of Medicine
Pifferi M, Baldini G, Marrazzini G, Baldini M, Ragazzo V, Pietrobelli A, et al. Benefits of immunotherapy with a standardized Dermatophagoides pteronyssinus extract in asthmatic children: a three-year prospective study. Allergy 2002; 57: 785-90. PubMed
Bufe A, Eberle P, Franke-Beckmann E, et al. Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy. J Allergy Clin Immunol 2009; 123: 167-73. PubMed
Wolf FM, Guevara JP, Grum CM, Clark NM, Cates CJ. Educational interventions for asthma in children (Cochrane review). Cochrane Database Syst Rev 2004;(4):CD000326. Cochrane (DOI)
Boyd M, Lasserson TJ, McKean MC, et al. Interventions for educating children who are at risk of asthma-related emergency department attendance. Cochrane Database of Syst Rev 2009, Issue 2. Art. No.: CD001290. DOI: 10.1002/14651858.CD001290.pub2. DOI
Guevara JP, Wolf FM, Grum CM, Clark NM. Effects of educational interventions for self management of asthma in children and adolescents: systematic review and meta-analysis. BMJ 2003; 326: 1308-9. British Medical Journal
Gøtzsche PC, Johansen HK. House dust mite control measures for asthma. Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No.: CD001187. DOI: 10.1002/14651858.CD001187.pub3. DOI
Murray CS, Foden P, Sumner H, et al. Preventing Severe Asthma Exacerbations in Children. A Randomized Trial of Mite-Impermeable Bedcovers. Am J Respir Crit Care Med 2017; 196: 150-8. pmid:28282501 PubMed
Kilburn S, Lasserson TJ, McKean M. Pet allergen control measures for allergic asthma in children and adults (Cochrane review). Cochrane Database Syst Rev 2004; (4): CD002989. Cochrane (DOI)
Stordal K, Johannesdottir GB, Bentsen BS, et al. Acid suppression does not change respiratory symptoms in children with asthma and gastro-oesophageal reflux disease. Arch Dis Child 2005; 90: 956-60. PubMed
Holbrook JT, Wise RA, Gold BD, et al. Lanzoprazole for children with poorly controlled asthma. JAMA 2012; 307: 373-80. Journal of the American Medical Association
Dogaru CM, Nyffenegger D, Pescatore AM, et al. Breastfeeding and childhood asthma: systematic review and meta-analysis. Am J Epidemiol 2014; 179: 1153-67. doi:10.1093/aje/kwu072 DOI
Jelding-Dannemand E, Malby Schoos AM, Bisgaard H. Breast-feeding does not protect against allergic sensitization in early childhood and allergy-associated disease at age 7 years. J Allergy Clin Immunol 2015; 136: 1302-08. pmid:25843315 PubMed
Factors influencing the relation of infant feeding to asthma and recurrent wheeze in childhood. Wright AL, Holberg CJ, Taussig LM, Martinez FD. Thorax 2001; 56: 192. doi:11182011
Sears MR, Greene JM, Willan AR, et al. Long-term relation between breastfeeding and development of atopy and asthma in children and young adults: a longitudinal study. Lancet 2002; 360: 901. pmid:12354471 PubMed
Gautier C, Charpin D. Environmental triggers and avoidance in the management of asthma. J Asthma Allergy 2017 Mar; 7: 10:47-56. pmid:28331347 PubMed
Custovic A, Wijk PG. The effectiveness of measures to change the indoor environment in the treatment of allergic rhinitis and asthma: ARIA update (in collaboration with GA(2)LEN). Allergy. 2005;60(9):1112–1115
Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2016. Online appendix, p. 57. Available from: www.ginasthma.org
Folkehelseinstituttet, nettpublikasjoner: Vaksinasjonsveilederen for helsepersonell. Pneumokokkvaksine. Sist oppdatert 11.12.2017. Siden besøkt 19.02.2018. www.fhi.no
Vaksinasjonsveilederen fra folkehelseinstituttet. Influensavaksine - veileder for helsepersonell. Sist oppdatert 02.06.2017 www.fhi.no
Cates CJ, Rowe BH. Vaccines for preventing influenza in people with asthma. Cochrane Database Syst Rev 2013;2:CD000364. The Cochrane Library
Folkehelseinstituttet: Vaksineanbefalinger influensasesongen 2018-2019. Sist oppdatert 19.09.2018. www.fhi.no
Bisgaard H, Stokholm J, Chawes BL, et al. Fish oil-derived fatty acids in pregnancy and wheeze and asthma in offspring. N Engl J Med 2016; 375: 2530-9. pmid:28029926 PubMed
Azad MB, Coneys JG, Kozyrskyj AL, et al. Probiotic supplementation during pregnanacy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis. BMJ 2013; 347: f6471. doi: http://dx.doi.org/10.1136/bmj.f6471
Pascual RM, Peters SP. The irreversible component of persistent asthma. J Allergy Clin Immunol 2009; 124: 883-90. pmid:19895980 PubMed
Karlsson CA, Isaksson M, Janson C. Inhalationssteroider kan ge sekundär binjurebarkssvikt. Läkartidningen 2014; 111: CTAZ
Loke YK, Blanco P, Thavarajah M, et al. Impact of Inhaled Corticosteroids on Growth in Children with Asthma: Systematic Review and Meta-Analysis. PLoS One 2015 Jul ; 10(7): e0133428. pmid:26191797 PubMed
Pedersen S. Clinical safety of inhaled corticosteroids for asthma in children: an update of long-term trials. Drug Saf 2006; 29(7): 599-612. pmid:16808552 PubMed
Pedersen S. Do inhaled corticosteroids inhibit growth in children?. Am J Respir Crit Care Med 2001 Aug; 164(4): 521-35. pmid:11520710 PubMed
Kjellman B, Gustafsson PM. Children with asthma followed up for 21 years; severity improved, but patients seldom grow out of asthma by adulthood. Läkartidningen 2000; 97: 4572-7.
Robinson P, Chang A. Asthma in children. BMJ Best Practice. Updatet Oct 05, 2016. bestpractice.bmj.com
Horak E, Lanigan A, Roberts A, et al. Longitudinal study of childhood wheezy bronchitis and asthma: outcome at age 42. BMJ 2003; 326: 422-3. PubMed
Long-term effects of budesonide or nedocromil in children with asthma. The Childhood Asthma Management Program Research Group. N Engl J Med 2000; 343: 1054-63. New England Journal of Medicine

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