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Lichen sclerosus et atrophicus: Årsak

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Årsaken er ukjent. Det kan forekomme flere tilfeller i samme familie av begge kjønn. Det antas at genetiske forhold og immunologiske forhold kan spille en rolle, og andre autoimmune sykdommer (som diabetes og stoffskiftesykdom) kan forekomme hos personer med lichen sclerosus. Hos tre til fem prosent av personer med denne tilstanden kan utslettet med tiden utvikle seg til hudkreft (plateepitelkarsinom).

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Dette dokumentet er basert på det profesjonelle dokumentet Lichen sclerosus et atrophicus (kvinner) . Referanselisten for dette dokumentet vises nedenfor

  1. De Luca DA, Papara C, Vorobyev A, Staiger H, Bieber K, Thaçi D, Ludwig RJ. Lichen sclerosus: The 2023 update. Front Med (Lausanne). 2023 Feb 16;10:1106318. PMID: 36873861 PubMed
  2. Powell JJ, Wojnarowska F: Lichen sclerosus. Lancet 1999; 353: 1777-83. PubMed
  3. Lewis FM, Tatnal FM, Velagni SS, et al. British Association of Dermatologists guidelines for the management of lichen sclerosus, 2018. Br J Dermatol 2018; 178: 839-53. PMID: 29313888 PubMed
  4. Singh N, Ghatage P. Etiology, Clinical Features, and Diagnosis of Vulvar Lichen Sclerosus: A Scoping Review. Obstet Gynecol Int. 2020 Apr 21;2020:7480754. PMID: 32373174 PubMed
  5. Krapf JM, Smith AB, Cigna ST, Goldstein AT. Presenting Symptoms and Diagnosis of Vulvar Lichen Sclerosus in Premenopausal Women: A Cross-Sectional Study. J Low Genit Tract Dis. 2022 Jul 1;26(3):271-275. PMID: 35533256. PubMed
  6. Kreuter A, Kryvosheyeva Y, Terras S, Moritz R, Möllenhoff K, Altmeyer P, et al. Association of autoimmune diseases with lichen sclerosus in 532 male and female patients. Acta Derm Venereol. 2013 Mar 27. 93(2):238-41. PMID: 23224274. PubMed
  7. Sherman V, McPherson T, Baldo M, Salim A, Gao XH, Wojnarowska F. The high rate of familial lichen sclerosus suggests a genetic contribution: an observational cohort study. J Eur Acad Dermatol Venereol. 2010 Sep;24(9):1031-4.PMID: 20202060. PubMed
  8. van der Meijden WI, Boffa MJ, Ter Harmsel B, Kirtschig G, Lewis F, Moyal-Barracco M, Tiplica GS, Sherrard J. 2021 European guideline for the management of vulval conditions. J Eur Acad Dermatol Venereol. 2022 Jul;36(7):952-972. PMID: 35411963.
  9. Krapf JM, Smith AB, Cigna ST, Goldstein AT. Presenting Symptoms and Diagnosis of Vulvar Lichen Sclerosus in Premenopausal Women: A Cross-Sectional Study. J Low Genit Tract Dis. 2022 Jul 1;26(3):271-275. PMID: 35533256. PubMed
  10. Stockdale CK, Boardman LA, Haefner HK, Lawson H. Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin, Number 224. Obstet Gynecol 2020; 136: e1-e14. pmid:32590724 PubMed
  11. Kirtschig G, Becker K, Günthert A, et al. Evidence-Based (S3) Guideline on (Anogenital) Lichen Sclerosus. J Eur Acad Dermatol Venereol 2015 Jul 22;EPub Ahead of Print . doi:10.1111/jdv.13136 DOI
  12. Thune T, Helgesen AL, Mai, HT, Peterson H, Moksnes LR - Vulvovaginale hudsykdommer. Veileder i gynekologi. metodebok.no metodebok.no
  13. Ellis E and Fischer G. Prepubertal-onset vulvar lichen sclerosus: The importance of maintenance therapy in long-term outcomes. Pediatr Dermatol 2015. doi: 10.1111/pde.12597 DOI
  14. Funaro D, Lovett A, Leroux N, Powell J. A double-blind, randomized prospective study evaluating topical clobetasol propionate 0.05% versus topical tacrolimus 0.1% in patients with vulvar lichen sclerosus. J Am Acad Dermatol. 2014 Jul;71(1):84-91. PMID: 24704090. PubMed
  15. Lee A, Fischer G. Diagnosis and treatment of vulvar lichen sclerosus: An update for dermatologists. Am J Clin Dermatol 2018; 19: 695-706. PMID: 29987650 PubMed
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