Hopp til innhold
NHI.no
Annonse

Overaktiv blære: Årsak

Innhold i artikkelen

Symptomene på overaktiv blære tilskrives unormalt kraftige nervesignaler fra urinblæren. Normalt skal behov for tømning melde seg når urinblæren begynner å bli full, men hos pasienter med overaktiv blære skjer dette når blæren bare er delvis fylt. Hvorfor dette skjer, vet vi ikke. Det er lansert teorier om både kroppslige og psykiske årsaker. Blant annet ser vi at hjerneskader (f.eks. etter hjerneslag, MS eller Parkinsons sykdom) kan forårsake overaktiv blære. 

Annonse

Vil du vite mer

Dette dokumentet er basert på det profesjonelle dokumentet Overaktiv blære . Referanselisten for dette dokumentet vises nedenfor

  1. Hunskår S. Behandling av overaktiv blære-syndrom. Tidsskr Nor Lægeforen 2005; 125: 2029-30. PubMed
  2. Abrams P, Cardozo L, Khoury S et al, red. Incontinence. 5rd International Consultation on Incontinence. 5 utg. Plymouth: Health Publication, 2013.
  3. European Association of Urology. Non-Oncology Guidelines. Nettside besøkt 14.02.2025. uroweb.org
  4. Norsk urologisk forenings anbefalinger for allmennleger. Overaktiv urinblære. Versjon mai 2018. Siden lest 26.02.2021. www.legeforeningen.no
  5. Lavelle JP, Karram M. Overactive bladder. Am J Med 2006; 19(3 Suppl 1): 1-2. www.amjmed.com
  6. Lavelle JP, Karram M, Chu FM, et al. Management of incontinence for family practice physicians. Am J Med 2006; 19(3 Suppl 1): 37-40. PMID: 16483867 PubMed
  7. Chu FM, Dmochowski R. Pathophysiology of overactive bladder. Am J Med 2006; 119(3 Suppl 1): 3-8. PMID: 16483862 PubMed
  8. Erdem N, Chu FM. Management of overactive bladder and urge urinary incontinence in the elderly patient. Am J Med 2006; 119(3 Suppl 1): 29-36. PMID: 16483866 PubMed
  9. Cui Y, Zong H, Yang C, et al. The efficacy and safety of mirabegron in treating OAB: a systematic review and meta-analysis of phase III trials. Int Urol Nephrol. 2014 ;46(1):275-84. doi: 10.1007/s11255-013-0509-9. DOI
  10. Yeowell G, Smith P, Nazir J, et al. Real-world persistence and adherence to oral antimuscarinics and mirabegron in patients with overactive bladder (OAB): a systematic literature review. BMJ Open. 2018. PMID: 30467131 PubMed
  11. Kelleher C, Hakimi Z, Zur R et al. Efficacy and Tolerability of Mirabegron Compared with Antimuscarinic Monotherapy or Combination Therapies for Overactive Bladder: A Systematic Review and Network Meta-analysis. Eur Urol. 2018 Sep;74(3):324-333. Epub 2018 Apr 23. PMID: 29699858. PubMed
  12. Nabi G, Cody JD, Ellis G, Hay-Smith J, Herbison GP. Anticholinergic drugs versus placebo for overactive bladder syndrome in adults. Cochrane Database of Systematic Reviews 2006, Issue 4. Art. No.: CD003781. DOI: 10.1002/14651858.CD003781.pub2. DOI
  13. Rai BP, Cody JD, Alhasso A, Stewart L. Anticholinergic drugs versus non‐drug active therapies for non‐neurogenic overactive bladder syndrome in adults. Cochrane Database of Systematic Reviews 2012, Issue 12. Art. No.: CD003193. DOI: 10.1002/14651858.CD003193.pub4. Accessed 22 February 2021. The Cochrane Library
  14. Madhuvrata P, Cody JD, Ellis G, Herbison GP, Hay‐Smith EJC. Which anticholinergic drug for overactive bladder symptoms in adults. Cochrane Database of Systematic Reviews 2012, Issue 1. Art. No.: CD005429. DOI: 10.1002/14651858.CD005429.pub2. Accessed 26 February 2021. The Cochrane Library
  15. Wagg A, Khullar V, Marschall-Kehrel D, et al. Flexible-dose fesoterodine in elderly adults with overactive bladder: results of the randomized, double-blind, placebo-controlled study of fesoterodine in an aging population trial. J Am Geriatr Soc 2013 Feb; 61(2): 185-93. PubMed
  16. Abrams P, Cardozo L, Khoury S et al, red. Incontinence. 3rd International Consultation on Incontinence. 3 utg. Plymouth: Health Publication, 2005.
  17. Stewart F, Gameiro LF, El Dib R, Gameiro MO, Kapoor A, Amaro JL. Electrical stimulation with non‐implanted electrodes for overactive bladder in adults. Cochrane Database of Systematic Reviews 2016, Issue 12. Art. No.: CD010098. DOI: 10.1002/14651858.CD010098.pub4. Accessed 26 February 2021. The Cochrane Library
  18. White N, Iglesia CB. Overactive Bladder. Obstet Gynecol Clin North Am. 2016 Mar;43(1):59-68. PMID: 26880508 PubMed
  19. Duthie JB, Vincent M, Herbison GP, Wilson DI, Wilson D. Botulinum toxin injections for adults with overactive bladder syndrome. Cochrane Database of Systematic Reviews 2011, Issue 12. Art. No.: CD005493. DOI: 10.1002/14651858.CD005493.pub3. Accessed 26 February 2021. The Cochrane Library
  20. Leng WW, Morrisroe SN. Sacral nerve stimulation for the overactive bladder. Urol Clin North Am 2006; 33: 491-501. PubMed
Annonse
Annonse