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Årsak

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Årsaken er ukjent. Symptomer og tegn skyldes økt hjernetrykk og opphovning av synsnerven (papilleødem). En rekke mekanismer er foreslått, men det finnes ingen åpenbar forklaring på hvordan tilstanden oppstår. Det er mulig at nedsatt tømning av veneblod fra hjernen kan ha en betydning.

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Antatte risikofaktorer er nylig vektøkning, noen medikamenter og systemiske sykdommer som Addison sykdom, hypotyreose, hypoparatyreoidisme, anemi, søvnapné, SLE, polycystisk ovariesyndrom.

Dette dokumentet er basert på det profesjonelle dokumentet Idiopatisk intrakraniell hypertensjon . Referanselisten for dette dokumentet vises nedenfor

  1. Gans MS. Idiopathic Intracranial Hypertension (IIH). Medscape, last updated Jun 08, 2022. emedicine.medscape.com
  2. Radhakrishnan K, Ahlskog JE, Cross SA, Kurland LT, O'Fallon WM. Idiopathic intracranial hypertension (pseudotumor cerebri). Descriptive epidemiology in Rochester, Minn, 1976 to 1990. Arch Neurol. 1993;50(1):78-80. PubMed
  3. Toscano S, Lo Fermo S, Reggio E, Chisari CG, Patti F, Zappia M. An update on idiopathic intracranial hypertension in adults: a look at pathophysiology, diagnostic approach and management. J Neurol. 2021;268(9):3249-3268. PubMed
  4. Friedman DI. Medication-induced intracranial hypertension in dermatology. Am J Clin Dermatol. 2005;6(1):29-37. PubMed
  5. Friedman DI, McDermott MP, Kieburtz K, et al. The idiopathic intracranial hypertension treatment trial: design considerations and methods. J Neuroophthalmol. 2014;34(2):107-117. PubMed
  6. Wall M, Kupersmith MJ, Kieburtz KD, et al. The idiopathic intracranial hypertension treatment trial: clinical profile at baseline. JAMA Neurol. 2014;71(6):693-701. PubMed
  7. Morden FTC, Tan C, Carrazana E, Viereck J, Liow KK, Ghaffari-Rafi A. Characterizing idiopathic intracranial hypertension socioeconomic disparities and clinical risk factors: A retrospective case-control study. Clin Neurol Neurosurg. 2021;208:106894. PubMed
  8. Quattrone A, Bono F, Fera F, Lavano A. Isolated unilateral abducens palsy in idiopathic intracranial hypertension without papilledema. Eur J Neurol. 2006;13(6):670-671. PubMed
  9. Agarwal P, Kumar M, Arora V. Clinical profile of cerebral venous sinus thrombosis and the role of imaging in its diagnosis in patients with presumed idiopathic intracranial hypertension. Indian J Ophthalmol. 2010;58(2):153-155. PubMed
  10. Sinclair AJ, Burdon MA, Nightingale PG, et al. Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. BMJ. 2010;341:c2701. PubMed
  11. NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee, Wall M, McDermott MP, et al. Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial. JAMA. 2014;311(16):1641-1651. PubMed
  12. Fonseca PL, Rigamonti D, Miller NR, Subramanian PS. Visual outcomes of surgical intervention for pseudotumour cerebri: optic nerve sheath fenestration versus cerebrospinal fluid diversion. Br J Ophthalmol. 2014;98(10):1360-1363. PubMed
  13. Kalyvas A, Neromyliotis E, Koutsarnakis C, et al. A systematic review of surgical treatments of idiopathic intracranial hypertension (IIH). Neurosurg Rev. 2021;44(2):773-792. PubMed
  14. Bouffard MA. Fulminant Idiopathic Intracranial Hypertension. Curr Neurol Neurosci Rep. 2020;20(4):8. PubMed
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