Hopp til innhold
NHI.no
Annonse

Munnsvelgkreft (orofarynkskreft): Symptomer

Innhold i artikkelen

I starten gir denne kreftformen svært få symptomer. Sykdommen kan derfor være vanskelig å oppdage. Det første man gjerne oppdager, er kuler på halsen og svelgbesvær. Etter hvert kan man merke økende smerter og blødninger fra sår på svulsten. Dessverre har sykdommen vart en stund når disse symptomene kommer, og det er risiko for at kreften har rukket å spre seg.

Annonse

Vil du vite mer

Dette dokumentet er basert på det profesjonelle dokumentet Orofarynkskreft . Referanselisten for dette dokumentet vises nedenfor

  1. Helsedirektoratet. Nasjonalt handlingsprogram med retningslinjer for diagnostikk, behandling og oppfølging av hode-/halskreft. 2020. ekstranett.helse-midt.no
  2. Chaturvedi AK, Anderson WF, Lortet-Tieulent J, Curado MP, Ferlay J, Franceschi S, Rosenberg PS, Bray F, Gillison ML. Worldwide trends in incidence rates for oral cavity and oropharyngeal cancers. J Clin Oncol. 2013 Dec 20;31(36):4550-9. doi: 10.1200/JCO.2013.50.3870. Epub 2013 Nov 18. PMID: 24248688 PubMed
  3. Nguyen NP, Nguyen LM, Thomas S, et al. Oral sex and oropharyngeal cancer: The role of the primary care physicians. Medicine (Baltimore). 2016 Jul;95(28):e4228. doi: 10.1097/MD.0000000000004228. PMID: 27428229 PubMed
  4. Kreftregisteret. Cancer in Norway 2022. Oslo: Kreftregisteret, mai 2023. www.kreftregisteret.no
  5. Mehanna H, Beech T, Nicholson T, et al. Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer—systematic review and meta-analysis of trends by time and region. Head Neck 2013;35:747–55
  6. Nasman A, Attner P, Hammarstedt L, Du J, Eriksson M, Giraud G, et al. Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma? Int J Cancer 2009; 125: 362-6. PubMed
  7. Moore KA, Mehta V. The growing epidemic of HPV-positive oropharyngeal carcinoma: A clinical review for primary care providers. J Am Board Fam Med 2015; 28: 498-503. PubMed
  8. Worden FP, Kumar B, Lee JS, Wolf GT, Cordell KG, Taylor JM, et al. Chemoselection as a strategy for organ preservation in advanced oropharynx cancer: response and survival positively associated with HPV16 copy number. J Clin Oncol 2008; 26: 3138-46. PubMed
  9. O'Rorke MA, Ellison MV, Murray LJ, Moran M, James J, Anderson LA. Human papillomavirus related head and neck cancer survival: a systematic review and meta-analysis. Oral Oncol 2012;48:1191–201
  10. McIlwain WR, Sood AJ, Nguyen SA, Day TA. Initial symptoms in patients with HPV-positive and HPV-negative oropharyngeal cancer. JAMA Otolaryngol Head Neck Surg 2014;140:441–7
  11. Dahlstrand H, Näsman A, Romanitan M, Lindquist D, Ramqvist T, Dalianis T. Human papillomavirus accounts both for increased incidence and better prognosis in tonsillar cancer. Anticancer Res 2008; 28: 1133-8. PubMed
  12. Lüscher M, Sengeløv L, et al. Oropharynxcancer. Lægehåndbogen, sist oppdatert 26.07.2017.
  13. Harris J, Wheeler R, Weber R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 2010; 363: 24-35. doi: 10.1056/NEJMoa0912217 DOI
  14. Fakhry C, Westra WH, Li S, Cmelak A, Ridge JA, Pinto H, et al. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 2008; 100: 261-9. PubMed
  15. Cramer JD, Grauer J, Sukari A et al. Incidence of Second Primary Lung Cancer After Low-Dose Computed Tomography vs Chest Radiography Screening in Survivors of Head and Neck Cancer: A Secondary Analysis of a Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021 Oct 28. Epub ahead of print. PMID: 34709369.
Annonse
Annonse